<p>Lead (Pb) is a pervasive environmental pollutant, prevalent in industrial areas, posing significant threats to both human and animal health. Exposure to Pb occurs through various avenues including industrial pollution, agricultural processing, and contaminated soil and feed. This cumulative toxin extensively accumulates in vital organs such as the brain, liver, kidney, bone, and hemopoietic system, instigating a spectrum of biochemical, physiological, behavioral, and morphological disorders. Central to the mechanism of Pb toxicity is oxidative damage. In response to this challenge, natural compounds with dual chelating and antioxidant properties have been explored for their potential in mitigating the adverse effects of Pb exposure.</p>