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- Volume 10, Number 3 (2023)

THE EQUATION OF THE STORM: A MATHEMATICAL ODYSSEY THROUGH JUPITER'S GREAT RED SPOT DYNAMICS

Leyla Javadova Mammadova, Farid Namazov Orujov

📅 November 28, 2023 | 📄 pp. 1-10

Self-organization, characterized by the ordered temporal and spatial evolution of events and structures, is a fundamental phenomenon in the cosmos. Theoretical studies of structure formation in the Universe heavily rely on modeling, as it often represents the only viable approach to validate theoretical predictions, particularly in the context of gravitational gas dynamics with its inherent nonlinearity. This holds true for the intricate processes involved in the development of hierarchical structures, entailing complex alterations in spatial geometry. Consequently, modeling has yielded a vast array of profound astrophysical insights and discoveries. A pivotal aspect of modeling gas dynamics and hydrodynamics is the...

NUMERICAL ALCHEMY: QUANTIFYING THE ELUSIVE DARK ENERGY AND DARK MATTER

Hans Dieter Wagner, Ingrid Maria Schmidt

📅 November 28, 2023 | 📄 pp. 11-18

The pursuit of a comprehensive understanding of the universe has led to the exploration of intriguing phenomena, such as dark energy, which remains an enigmatic force responsible for the accelerated expansion of the cosmos. In this work, we derive a novel formula for calculating dark energy, unveiling a fresh perspective on this elusive cosmic component. Our approach hinges on the fundamental concepts of the Planck time (tp) and the oscillatory nature of dark energy, which we establish as conforming to the Planck/Einstein formula. Through this derivation, we demonstrate how the quotient h/tp encapsulates the essential energy information required for the...

STRATEGIC SYNTHESIS: RING C OXYGENATED CHOLESTEROL DERIVATIVES AS KEY PLAYERS IN INHIBITING STEROL BIOSYNTHESIS

Samantha Lynn Anderson, Budi Santoso Widodo

📅 November 28, 2023 | 📄 pp. 19-28

Oxysterols, defined as sterols with an additional oxygen function, have emerged as compounds of significant interest due to their diverse and multifaceted biological properties. This review explores the various aspects of oxysterols, including their cytotoxicity, atherogenicity, carcinogenicity, mutagenicity, hypocholesterolemia, and effects on specific enzymes. These compounds are not only found widely distributed in nature but are also present in animal tissues and food items. Furthermore, oxysterols have been isolated from natural drugs employed in traditional medicine for cancer treatment. In this review, we delve into the biological implications and sources of oxysterols, shedding light on their potential impact on human...

DISTANT TRANSFORMATIONS: CHROMIC ANHYDRIDES' ROLE IN STEROID SIDE CHAIN MODIFICATION

Elizabeth Reynolds

📅 November 28, 2023 | 📄 pp. 29-47

Natural steroids feature diverse side chains in terms of their structure and composition, presenting unique challenges for organic chemists [3-6]. The modification of existing side chains, even those containing unsaturation, is relatively straightforward compared to the intricate and time-consuming process of constructing new side chains. Many naturally occurring steroids possess saturated side chains devoid of useful functionalities, complicating the chemist's task [1,2]. This study focuses on the intricate field of functionalizing saturated side chains in steroids, with a particular emphasis on cholesterol. Through rigorous chemical synthesis techniques, we aim to address the complexities surrounding this problem and contribute to a...