- Volume 10, Number 2 (2023)
CRACKING THE REDOX CODE: GAZIANTEP'S CONTRIBUTION TO UNDERSTANDING METABOLIC DISORDERS
Zeynep Gülseren Gürpınar
Metabolic disorders, characterized by disruptions in energy and redox balance, represent a significant burden on human health. Among these, Maple Syrup Urine Disease (MSUD) and Phenylketonuria (PKU) are prominent examples of autosomal recessive disorders arising from deficiencies in branched chain α-ketoacid dehydrogenase complex and phenylalanine hydroxylase activity, respectively (Stepien, et al., 2017). While reactive oxygen species (ROS) and reactive nitrogen species (RNS) are essential for normal physiological processes, their dysregulation can lead to oxidative and nitrosative stress, causing cellular damage when the antioxidant defense system is compromised or when there is an increase in the production of these free radicals...
WATER CLARITY, DATA PRECISION: DIRECT DISTILLATION TECHNIQUES FOR ACCURATE CARBON DIOXIDE MEASUREMENT
Fatima Ahmed Al-Mansour
High-pressure solvent extraction (HPSE) has gained prominence in various industries, including chemical, food, and pharmaceutical sectors, owing to its numerous advantages. In this study, we explore the application of HPSE, particularly using CO2 as the solvent, for the extraction of valuable compounds from marigold (Calendula officinalis L.), a plant with a wide range of applications in traditional medicine and modern formulations. Conventional extraction processes, such as steam distillation and solvent extraction, often entail additional separation steps and exhibit lower selectivity when compared to CO2-based HPSE. The unique characteristics of HPSE, including lower operating temperatures and reduced water content, contribute to...
ELEGANT ARRANGEMENTS: A CRYSTALLOGRAPHIC PERSPECTIVE ON THE BIS[1-METHOXY-2,2,2-TRIS-(PYRAZOL-1-YLΚN2) ETHANE]-COBALT(II) BIS-PERCHLORATE COMPLEX
Olivia Mae Turner
Inorganic chemistry research in the modern era predominantly revolves around the captivating realm of coordination chemistry. A fundamental component of this field is the study of transition metals, which are characterized by their incomplete d or f subshells in their elemental or ionic states (Huheey et al., 1993). This introduction sets the stage for exploring the multifaceted aspects of transition metals in coordination chemistry research. Transition metals, positioned within the same period of the periodic table, exhibit gradual changes in their atomic and ionic radii as well as ionization potentials from one element to the next. This subtle progression creates...