Antibacterial potential of crab shell extract on Klebsiella pneumoniae and Proteus mirabilis

Abstract

This study aimed to evaluate the antibacterial potential of crab shell extract, a by-product of the seafood industry in Nigeria, on Klebsiella pneumoniae and Proteus mirabilis. The antibacterial susceptibility of both bacteria was tested using crab shell extract and compared with commonly used antibiotics. Results demonstrated that only K. pneumoniae was sensitive to the crab shell extract while P. mirabilis was resistant. The highest zone of inhibition for K. pneumoniae was recorded for isolate Kp2 at a concentration of 200μg/ml. Chitin and chitosan, two derivatives from crab shell extract, were also explored for their antibacterial properties. Chitosan, a non-toxic biodegradable polymer of D-glucosamine, has bacteriostatic, immunologic, antitumor, cicatrizant, haemostatic, and anticoagulant properties. This study highlights the potential of crab shell extract as an antibacterial agent and illuminates its economic potential in Nigeria. The study provides insights for further research into the development of new drugs or treatment methods using crab shell extract.